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Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys

Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys

Lee, Quintin; Padula, Matthew P.; Pinello, Natalia; Williams, Simon H.; O'Rourke, Matthew B.; Fumagalli, Marcilio Jorge; Orkin, Joseph D.; Song, Renhua; Shaban, Babak; Brenner, Ori; Pimanda, John E.; Weninger, Wolfgang; Souza, William Marciel de; Melin, Amanda D.; Wong, Justin J.-L.; Crim, Marcus J.; Monette, Sébastien; Roediger, Ben; Jolly, Christopher J.
URI: https://doi.org/10.1371/journal.ppat.1008262
http://hdl.handle.net/11606/2260
Date: 2020-01-23

Abstract:

Mouse kidney parvovirus (MKPV) is a member of the provisional genus Chapparvovirus that causes renal disease in immune-compro mised mice, with a disease course reminiscent of polyomavirus-assoc iated nephropathy in immune-supp ressed kidney transplant patients

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